Aptah's drug discovery and design process in based on oligonucleotides antisense (AOs) technology.
Natural dynamic between DNA, mRNA and Disease-Associated Protein
Current Antisense Gene Therapy
Current Antisense therapies act on the pre-mRNA by silencing undesired segments of the DNA in order to avoid the propagation of errors caused by possible genetic instabilities. Within the "silencing method" however, it may occur that certain information within the targeted segment is eliminated instead of corrected. As a consequence this can cause damage and in extreme cases even cellular death.
APTAH Antisense Gene Therapy
Aptah's Antisense technology is based on the modulation of the pre-mRNA (instead of silencing). With this we are able to determine with precision how proteins are synthesized without activating any collateral effects and without altering the DNA.